The Pharmacomer™ Technology Platform developed by Surface Logix stems from the biophysical and surface chemistry work pioneered by Professor George Whitesides at Harvard University.

Below is a select list of publications in biosurface chemistry, biology and soft lithography.

 
     
 

BioSurface Chemistry

  • CHEMBIOCHEM No. 7/8: 590-593 (2001) "Electroactive Monolayer Substrates that Selectively Release Adherent Cells" by Woon-Seok Yeo, Christian D. Hodneland, and Milan Mrksich
  • Proc. Nat. Acad. Sci. Vol. 98 No. 11: 5992-5996 (May 22, 2001) "Using Electroactive Substrates to Pattern the Attachment of Two Different Cell Populations" by Muhammad N. Yousaf, Benjamin T. Houseman, and Milan Mrksich
  • CHEM. SOC. REV. 29: 267-273 (2000) "A Surface Chemistry Approach to Studying Cell Adhesion" by Milan Mrksich
  • J. AM. CHEM. SOC. 121: 4286-4287 (1999) "Diels-Alder Reaction for the Selective Immobilization of Protein to Electroactive Self-Assembled Monolayers" by Muhammad N. Yousaf, and Milan Mrksich
  • J. AM. CHEM. SOC. Vol. 117 No. 48: 12009-12010 (1995) "Biospecific Adsorption of Carbonic Anhydrase to Self-Assembled Monolayers of Alkanethiolates That Present Benzenesulfonamide Groups on Gold" by Milan Mrksich, Jocelyn R. Grunwell, and George M. Whitesides

Biology

  • NATURE 411: 1016 (June 28, 2001) "Subcellular Positioning of Small Molecules" by Shuichi Takayama, Emanuele Ostuni, Philip LeDuc, Keiji Naruse, Donald E. Ingber, and George M. Whitesides
  • LANGMUIR 17: 2828-2834 (2001) "Selective Deposition of Proteins and Cells in Arrays of Microwells" by Emanuele Ostuni, Christopher S. Chen, Donald E. Ingber, and George M. Whitesides
  • Proc. Nat. Acad. Sci. Vol. 97 No. 6: 2408-2413 (March 14, 2000) "Patterned Deposition of Cells and Proteins Onto Surfaces by Using Three-Dimensional Microfluidic Systems" by Daniel T. Chiu, Noo Li Jeon, Sui Huang, Ravi S. Kane, Christopher J. Wargo, Insung S. Choi, Donald E. Ingber, and George Whitesides
  • BIOMATERIALS 20: 2363-2376 (1999) "Patterning Proteins and Cells Using Soft Lithography" by Ravi S. Kane, Shuichi Takayama, Emanuele Ostuni, Donald E. Ingber, and George M. Whitesides
  • SCIENCE 276: 1425-1428 (May 30, 1997) "Geometric Control of Cell Life and Death" by Christopher S. Chen, Milan Mrksich, Sui Huang, George M. Whitesides, and Donald E. Ingber

Soft Lithography

  • ANNU. REV. BIOMED. ENG. 3:335-373 (2001) "Soft Lithography in Biology and Biochemistry" by George M. Whitesides, Emanuele Ostuni, Shuichi Takayama, Xingyu Jiang, and Donald E. Ingber
  • SCIENCE 285: 83-85 (July 2, 1999) "Microfabrication Inside Capillaries Using Multiphase Laminar Flow Patterning" by Paul J. A. Kenis, Rustem F. Ismagilov, and George M. Whitesides
  • PHYSICS WORLD (May 1998) "Soft Lithography and Microfabrication" by Scott Brittain, Kateri Paul, Xiao-Mei Zhao, and George Whitesides
  • ANGEW. CHEM. INT. ED. 37: 550-575 (1998) "Soft Lithography" by Younan Xia and George M. Whitesides
  • NATURE 376: 581-584 (August 17, 1995) "Polymer Microstructures Formed by Moulding in Capillaries" by Enoch Kim, Younan Xia, and George M. Whitesides